Source:http://www.reactome.org/biopax/48887BiochemicalReaction4367
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| biopax3:comment |
3,7,24THCA (25(R) 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate), coenzyme A, and ATP react to form the CoA conjugate of 3,7,24THCA, AMP, pyrophosphate and water. This cytosolic reaction is catalyzed by SLC27A2 (VLCS). SLC27A5 (BACS) also catalyzes this reaction; the relative contributions of the two enzymes to de novo bile acid synthesis in vivo are not certain (Mihalik et al. 2002).,
Authored: D'Eustachio, P, 2007-02-23 20:35:09,
Edited: D'Eustachio, P, 2007-02-23 20:35:09,
Reviewed: D'Eustachio, P, 2007-04-30 14:43:26
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| biopax3:displayName |
3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS)
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| biopax3:name |
3,7,24THCA + ATP + CoASH => 3,7,24THCA-CoA + AMP + pyrophosphate + H2O (SLC27A2 "VLCS")
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| biopax3:eCNumber |
6.2.1.3
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