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Authored: D'Eustachio, P, 2010-03-14, Edited: D'Eustachio, P, 2010-05-08, Elongation of very long chain fatty acids protein 3 (ELOVL3) catalyzes the reaction of palmitoyl-CoA and malonyl-CoA to form 3-oxooctadecanoyl-CoA (3-oxostearoyl-CoA), CO2, and CoASH. Indirect data from studies of transfected cells expressing ELOVL3 are consistent with its localization to the endoplasmic reticulum and activity on palmitoyl-CoA (Kobayashi et al. 2007).
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palmitoyl-CoA + malonyl-CoA => 3-oxooctadecanoyl-CoA (3-oxostearoyl-CoA) + CO2 + CoASH [ELOVL3]
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