Source:http://www.reactome.org/biopax/48887BiochemicalReaction4074
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Authored: Jassal, B, 2011-10-19,
Edited: Jassal, B, 2011-10-19,
Heparanase 2 (HPSE2) (McKenzie et al. 2000) is a membrane-bound endoglycosidase that cleaves heparan sulfate (HS) from its HS proteoglycan (HSPG), either in the extracellular matrix or the basement membranes of cells. Defects in HPSE2 are the cause of urofacial syndrome (UFS) (MIM:236730) (Daly et al. 2010, Pang et al. 2010).,
Reviewed: D'Eustachio, P, 2012-03-28
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Heparanase 2 (HPSE2) cleaves heparan sulfate from its proteoglycan (plasma membrane)
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