Source:http://www.reactome.org/biopax/48887BiochemicalReaction3987
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Reviewed: Harris, RA, 2008-09-10 18:47:12,
The fructose 2,6-bisphosphatase activity of cytosolic phosphofructokinase 2/fructose-2,6-bisphosphatase catalyzes the hydrolysis of fructose 2,6 bisphosphate to form fructose 6-phosphate. Fructose 2,6 bisphosphate is a key allosteric regulator of PFK1. In its absence the activity of PFK1 is reduced while fructose 1,6-bisphosphatase is activated, thus inhibiting glycolysis and favoring gluconeogenesis (Pilkis et al. 1995).
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Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate
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3.1.3.46
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