Source:http://www.reactome.org/biopax/48887BiochemicalReaction393
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Authored: Jassal, B, 2009-06-12,
Edited: Jassal, B, 2009-06-12,
Reviewed: He, L, 2009-08-24,
Two genes (SLC12A1 and SLC12A2) encode Na+,K+/2Cl- cotransporters (NKCC2 and NKCC1 respectively). SLC12A1 (Simon DB et al, 1996) is kidney-specific whilst SLC12A2 (Payne JA et al, 1995) is ubiquitously expressed. Two Cl- ions are electroneutrally transported into cells with a Na+ ion and a K+ ion.
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Na+, K+/2Cl- cotransport
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