Source:http://www.reactome.org/biopax/48887BiochemicalReaction3928
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Authored: Orlic-Milacic, M, 2012-04-04,
Edited: Jassal, B, 2012-04-10,
Recombinant mouse Uchl5 (Uch37) exogenously expressed in HEK293 cells deubiquitinates recombinant human TGFBR1. This stabilizes TGFBR1 and prolongs signaling by TGF-beta receptor complex. Deubiqutination of Smad7 has not been examined in this context (Wicks et al. 2005).,
Reviewed: Huang, Tao, 2012-05-14
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Uchl5 deubiquitinates TGFBR1
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3.1.2.15
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