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Authored: Blackburn, EH, Seidel, J, 2006-03-09 19:41:08, Reviewed: Price, C, 2006-07-13 18:33:38, The binding of the primer recognition complex involves the loading of proliferating cell nuclear antigen (PCNA). Replication Factor C transiently opens the PCNA toroid in an ATP-dependent reaction, and then allows PCNA to re-close around the double helix adjacent to the primer terminus. This leads to the formation of the "sliding clamp".
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Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere
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