Source:http://www.reactome.org/biopax/48887BiochemicalReaction3827
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During interphase, cyclin B1:Cdc2 shuttles continuously in and out of the nucleus. Cyclin B1:Cdc2 is transported into the nucleus by an unusual mechanism that requires importin b but not importin a or Ran. Dissociation of the cyclin-B1:Cdc2:importin complex in the nucleus requires ATP and involves other yet unidentified nuclear factors (Takizawa et al.,1991).
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Translocation of Cyclin B1:phospho-Cdc2 complexes to the nucleus
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