Source:http://www.reactome.org/biopax/48887BiochemicalReaction3821
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The human Wee1 kinase phosphorylates Cdc2 on tyrosine 15 inactivating the cyclin:CDK complex (Watanabe et al., 1995).
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Wee1-mediated phosphorylation of Cyclin A:phospho-Cdc2 complexes
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