Source:http://www.reactome.org/biopax/48887BiochemicalReaction3817
| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
Cyclin A is synthesized and associates with Cdc2 in G1. Cyclin dependent kinases are themselves catalytically inactive due to the fact that their active sites are blocked by a portion of the CDK molecule itself. Binding to their corresponding cyclin partner results in a conformational change that partially exposes the active site.
|
| biopax3:xref | |
| biopax3:dataSource | |
| biopax3:displayName |
Formation of Cyclin A:Cdc2 complexes
|
| biopax3:left | |
| biopax3:right |