Source:http://www.reactome.org/biopax/48887BiochemicalReaction3810
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At the beginning of this reaction, 1 molecule of 'Cyclin D1:Cdk4', and 1 molecule of 'ATP' are present. At the end of this reaction, 1 molecule of 'phospho(T286)-Cyclin D1:Cdk4', and 1 molecule of 'ADP' are present.<br><br> This reaction takes place in the 'nucleus' and is mediated by the 'kinase activity' of 'glycogen synthase kinase-3 beta'.<br>
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Phosphorylation of Cyclin D1 at T286 by glycogen synthase kinase-3 beta
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