Source:http://www.reactome.org/biopax/48887BiochemicalReaction3794
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Authored: Pagano, M, 2006-09-19 08:23:10,
Edited: Matthews, L, 2006-09-28 04:25:14,
Phosphorylation of cyclin-dependent kinases (CDKs) by the CDK-activating kinase (CAK) is required for the activation of the CDK kinase activity. The association of p21/p27 with the Cyclin A/E:Cdk2 complex prevents CAK mediated phosphorylation of Cdk2 (Aprelikova et al., 1995).,
Reviewed: Coqueret, O, 2006-10-06 08:59:06
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CAK-mediated phosphorylation of Cyclin E:Cdk2
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