Source:http://www.reactome.org/biopax/48887BiochemicalReaction3767
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Authored: Orlic-Milacic, Marija, 2011-06-14,
Reviewed: MacPherson, D, 2011-08-25,
p107 (RBL1) in complex with E2F4 and DP1/2 binds to cyclin A or cyclin E in complex with CDK2 through its conserved LFG pocket domain motif and amino terminus, leading to inhibition of CDK2 kinase activity and suppression of cellular growth.
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p107 (RBL1) in complex with E2F4:DP1/2 binds to cyclin E/A:CDK2
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