Source:http://www.reactome.org/biopax/48887BiochemicalReaction3764
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Authored: Orlic-Milacic, Marija, 2011-06-14,
Reviewed: MacPherson, D, 2011-08-25,
p130 (RBL2) in complex with E2F4 or E2F5 and DP1 or DP2 recruits histone deacetylase HDAC1, probably in complex with other chromatin modification factors, and represses transcription of E2F target promoters during G0 in quiescent cells.
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Recruitment of HDAC1 by p130 (RBL2)
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HDAC1 + p130(RBL2):E2F4/5:DP1 => HDAC1-p130(RBL2):E2F4/5:DP1
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