Source:http://www.reactome.org/biopax/48887BiochemicalReaction3763
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Authored: Orlic-Milacic, Marija, 2011-06-14,
Reviewed: MacPherson, D, 2011-08-25,
p107 (RBL1) in complex with E2F4 and DP1 or DP2 recruits histone deacetylase HDAC1 (possibly in complex with other chromatin modification proteins) through LXCXE-like motif, shared by pocket proteins, to repress transcription of E2F target genes in early G1.
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Recruitment of HDAC1 by p107 (RBL1)
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HDAC1 + p107(RBL1):E2F4:DP1 => HDAC1-p107(RBL2):E2F4:DP1
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