Source:http://www.reactome.org/biopax/48887BiochemicalReaction3669
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Authored: Shamovsky, V, 2009-12-16,
Edited: Shamovsky, V, 2009-12-16,
In human, polyubiquitinated TRAF6 activates TAK1 by binding to the ubiquitin receptors TAB2 and TAB3. This binding leads to autophosphorylation and activation of TAK1.,
Reviewed: Gay, NJ, 2006-04-24 16:48:17
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Activated TRAF6 recruits TAK1complex by binding to ubiquitin receptors of TAB2/TAB3
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6.3.2.19
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