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Authored: Geiger, B, Horwitz, R, 2008-05-07 08:30:32, Edited: Garapati, P V, 2008-03-11 10:20:45, Laminins are a group of large, adhesive glycoproteins found in all basement membranes. Laminins contribute to the structure, stability and physical characteristics of basement membrane and also induce a multitude of cellular responses, including migration, cell polarization and influence cell proliferation and differentiation. The alpha1beta1 integrin is one of the laminin-1 (EHS-laminin) receptors that link the ECM to the cell interior and can activate several pathways., Reviewed: Yamada, K, Humphries, MJ, Hynes, R, 2008-05-07 08:53:37
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Interaction of integrin alpha1beta1 with Laminin-1
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