Source:http://www.reactome.org/biopax/48887BiochemicalReaction3547
| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
Authored: Le Novere, N, Jassal, B, 2004-03-31 12:22:05,
Edited: Jassal, B, 2008-11-06 10:17:49,
Reviewed: Castagnoli, L, 2008-11-06 12:55:54,
The phospholipase C (PLC) family of enzymes is both diverse and complex. The isoforms beta, gamma and delta (each have subtypes) make up the members of this family. One type, PLC-beta1, hydrolyzes phosphatidylinositol bisphosphate (PIP2) into two second messengers, inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG). IP3 mobilizes intracellular calcium stores while DAG activates protein kinase C isoforms which are involved in regulatory functions.
|
| biopax3:xref | |
| biopax3:dataSource | |
| biopax3:displayName |
PIP2 hydrolysis
|
| biopax3:eCNumber |
3.1.4.11
|
| biopax3:left | |
| biopax3:right |