Source:http://www.reactome.org/biopax/48887BiochemicalReaction3490
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biopax3:comment |
Authored: Jassal, B, 2009-02-13 11:37:11,
Edited: Jassal, B, 2009-02-13 11:37:11,
Reviewed: D'Eustachio, P, 2009-03-02 09:24:35,
The liganded receptor undergoes a conformational change, generating a signal that is propagated in a manner that is not completely understood to the the G-protein. This stimulates the exchange of GDP for GTP in the G-protein alpha subunit, activating the G-protein.
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biopax3:xref |
http://identifiers.org/pubmed/12106601,
http://identifiers.org/pubmed/12860470,
http://identifiers.org/pubmed/2553705,
http://identifiers.org/pubmed/3086311,
http://identifiers.org/pubmed/3113327,
http://identifiers.org/pubmed/3127824,
http://identifiers.org/pubmed/9032437,
http://identifiers.org/pubmed/9651336,
urn:biopax:UnificationXref:REACTOME DATABASE ID_379044,
urn:biopax:UnificationXref:REACTOME_REACT_17008_5
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biopax3:displayName |
Liganded Gs-activating GPCR acts as a GEF for Gs
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