Source:http://www.reactome.org/biopax/48887BiochemicalReaction3441
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Authored: Jassal, B, 2009-04-14 09:13:21,
Edited: Jassal, B, 2009-04-14 09:13:21,
Reviewed: D'Eustachio, P, 2009-05-29 07:44:22,
The P2Y10 receptor is expressed during myeloid differentiation of HL60 cells (Adrian K et al, 2000) and is the first dual lysophospholipid receptor, able to bind both sphingosine-1-phosphate (S1P) and lysophosphatidic acid (LPA) (Murakami M et al, 2008). The effects of this receptor are mediated by coupling with the G protein alpha q/11 subunit.
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P2Y10 receptor can bind to LPA
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