Source:http://www.reactome.org/biopax/48887BiochemicalReaction3438
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Authored: Jassal, B, 2009-04-14 09:13:21,
Edited: Jassal, B, 2009-04-14 09:13:21,
Reviewed: D'Eustachio, P, 2009-05-29 07:44:22,
The P2Y5 receptor (Lee CW et al, 2006) binds lysophosphatidic acid (LPA). Its effects are mediated by coupling with the G protein alpha G q/11 and G12/13 subunits (Lee CW et al, 2006). Mutations in the P2RY5 gene cause a rare, inherited form of hair loss called Hypotrichosis simplex. It is the first receptor in humans known to play a role in hair growth (Pasternack SM et al, 2008).
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P2Y5 receptor can bind to LPA
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