Source:http://www.reactome.org/biopax/48887BiochemicalReaction3432
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Authored: Jassal, B, 2009-03-26 15:30:13,
Edited: Jassal, B, 2009-03-26 15:30:13,
Reviewed: D'Eustachio, P, 2009-05-29 07:44:22,
The cysteinyl-leukotrienes (cys-LTs) are potent smooth muscle contractile agents mediating bronchoconstriction. Examples are LTC4, LTD4 and LTE4. There are two human cys-LT receptors, 1 (Lynch KR et al, 1999) and 2 (Heise CE et al, 2000). They mediate their effects via coupling to the G protein alpha q/11 subunit (Sarau HM et al, 1999).
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CysLT receptors can bind cysteinyl leukotrienes
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