Source:http://www.reactome.org/biopax/48887BiochemicalReaction3417
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Authored: Jassal, B, 2009-02-12 10:33:32,
Edited: Jassal, B, 2009-02-12 10:33:32,
Reviewed: D'Eustachio, P, 2009-03-02 09:24:35,
The 5-HT-2 receptors mediate many of the central and peripheral physiologic functions of serotonin. There are three subtypes; 2A (Stam NJ et al, 1992), 2B (Kursar JD et al, 1994; Schmuck K et al, 1994) and 2C (Stam NJ et al, 1994). The actions of these receptors are mediated by coupling with the G protein alpha-q/11 subtype which activates phospholipase C, increasing cellular levels of inositol trisphosphate (IP3) and diacylglycerol (DAG) (Lucaites VL et al, 1996).
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http://identifiers.org/pubmed/1330647,
http://identifiers.org/pubmed/7895773,
http://identifiers.org/pubmed/8078486,
http://identifiers.org/pubmed/8143856,
http://identifiers.org/pubmed/8809227,
urn:biopax:UnificationXref:REACTOME DATABASE ID_390930,
urn:biopax:UnificationXref:REACTOME_REACT_16879_2
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5-HT2 receptor can bind serotonin
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