Source:http://www.reactome.org/biopax/48887BiochemicalReaction3366
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Authored: Jassal, B, 2008-08-21 14:07:16,
Edited: D'Eustachio, P, 2008-09-01 11:58:31,
Reviewed: Bockaert, J, 2008-09-01 12:04:13,
These three receptors can all bind the CC chemokine CCL16. CCR1 was the first CC chemokine receptor identified (Neote K et al, 1993) and can bind multiple chemokines. CCR1 is found on blood lymphocytes and monocytes. CCR2 is found on monocytes, B cells, activated memory T cells and basophils (Yamagami S et al, 1994). CCR8 is found mainly in the thymus (Tiffany HL et al, 1997).
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Receptors CCR1, 2 and 8 bind CCL16 ligand
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