Source:http://www.reactome.org/biopax/48887BiochemicalReaction3360
| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
Authored: Jassal, B, 2008-08-21 14:07:16,
CXCR1 (high affinity interleukin-8 receptor A) (Holmes WE et al, 1991) is closely related to CXCR2. They recognize CXC chemokines that possess an E-L-R amino acid motif immediately adjacent to their CXC motif. CXCL8 (interleukin-8, IL-8) (Matsushima K et al, 1988) and CXCL6 (Rovai LE et al, 1997) can both bind CXCR1 in humans and elicit various effects. CXCL8 attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. CXCL6 is a chemotactic factor for neutrophil granulocytes.,
Edited: D'Eustachio, P, 2008-09-01 11:58:31,
Reviewed: Bockaert, J, 2008-09-01 12:04:13
|
| biopax3:xref | |
| biopax3:dataSource | |
| biopax3:displayName |
Receptor CXCR1 binds CXCL6 and CXCL8 ligands
|
| biopax3:left | |
| biopax3:right |