Source:http://www.reactome.org/biopax/48887BiochemicalReaction3349
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Authored: Jassal, B, 2008-08-21 14:07:16,
Edited: D'Eustachio, P, 2008-09-01 11:58:31,
Reviewed: Bockaert, J, 2008-09-01 12:04:13,
The Duffy blood group system consists of two antigens defining four phenotypes (Marsh WL, 1975). Duffy antigen/receptor for chemokines (DARC) (Chaudhuri A et al, 1993) carries the Duffy (Fy) blood group and acts as a widely expressed promiscuous chemokine receptor. The chemokine interleukin-8 is one example shown here.
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DARC is a non-specific receptor for many chemokines
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