Source:http://www.reactome.org/biopax/48887BiochemicalReaction3312
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Authored: Jassal, B, 2004-12-15 13:08:03,
Edited: D'Eustachio, P, 2012-02-06,
Edited: Orlic-Milacic, M, 2012-02-10,
NOTCH1 is activated by JAG2 ligand expressed on a neighboring cell. When the mouse myoblast cell line C2C12 expressing exogenous human NOTCH1 is grown with NIH3T3 cells expressing exogenous human JAG2, myogenic differentiation is inhibited and a NOTCH1 polypeptide that corresponds to the NOTCH intracellular domain appears (Luo et al. 1997).,
Reviewed: Haw, R, 2012-02-06,
Reviewed: Joutel, A, 2004-12-15
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NOTCH1 binds JAG2
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