Source:http://www.reactome.org/biopax/48887BiochemicalReaction3252
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Authored: Orlic-Milacic, M, 2012-04-04,
Edited: Jassal, B, 2012-04-10,
Reviewed: Huang, Tao, 2012-05-14,
STRAP (serine-threonine kinase receptor-associated protein) binds to the activated TGF-beta receptor complex. In in vitro studies, STRAP is able to bind both TGFBR1 and TGFBR2 (Datta et al. 1998). This was deduced from experiments in which a recombinant mouse Strap and recombinant human TGFBR1 and TGFBR2 were expressed in COS1 cells.
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STRAP binds phosphorylated TGF-beta receptor complex
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