Source:http://www.reactome.org/biopax/48887BiochemicalReaction3245
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Authored: Heldin, CH, Moustakas, A, Huminiecki, L, Jassal, B, 2006-02-02,
Edited: Jassal, B, 2006-01-18 10:19:52,
Reviewed: Heldin, CH, 2006-04-18 14:26:12,
Reviewed: Huang, Tao, 2012-05-14,
The mature dimeric TGF-beta-1 (TGFB1) binds with high affinity to its signaling receptor, the type II receptor serine/threonine kinase (TGFBR2). The type II receptor is known to form dimeric complexes even in the absence of TGF-beta-1.
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Dimeric TGFB1 binds to TGFBR2 homodimer
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Dimeric TGF-beta-1 binds to the receptor
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