Source:http://www.reactome.org/biopax/48887BiochemicalReaction318
| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
The mRNA-bound ribosomal complex moves along the 5'-untranslated region (5'-UTR) of the mRNA from its initial site to the initiation codon to form a 48S complex, in which the initiation codon (AUG) is base paired to the anticodon of the Met-tRNAi. It is not known whether eIF4A (or another ATPase, such as DED1) facilitates scanning by melting mRNA secondary structures or by actively propelling the ribosome.
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| biopax3:xref |
http://identifiers.org/pubmed/10364207,
http://identifiers.org/pubmed/592399,
http://identifiers.org/pubmed/641056,
http://identifiers.org/pubmed/7000367,
http://identifiers.org/pubmed/8943342,
http://identifiers.org/pubmed/9045610,
urn:biopax:UnificationXref:REACTOME DATABASE ID_72621,
urn:biopax:UnificationXref:REACTOME_REACT_1516_1
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| biopax3:dataSource | |
| biopax3:displayName |
Ribosomal scanning
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| biopax3:left | |
| biopax3:right |