Source:http://www.reactome.org/biopax/48887BiochemicalReaction3130
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Authored: Garapati, P V, 2011-07-11,
Edited: Garapati, P V, 2011-07-11,
Reviewed: Rönnstrand, L, 2011-08-22,
Vav1, once activated by PIP3 binding and phosphorylation by Src kinases, stimulates the GDP/GTP exchange activity of Rac. Vav1 is selective for Rac and catalyses exchange of bound GDP for GTP.
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Activation of RAC1
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