Source:http://www.reactome.org/biopax/48887BiochemicalReaction3115
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Authored: Garapati, P V, Jassal, B, 2008-11-24 10:14:27,
Edited: Garapati, P V, Jassal, B, 2008-11-24 10:14:27,
Grb7 an adapter protein contains a single SH2 domain, a pleckstrin homology (PH) domain, and a proline-rich region. Similar to Grb2, Grb7 interacts with phosphorylated tyrosines in pYXNX motifs, including Tyr716 and Tyr775 of the PDGF beta-receptor.,
Reviewed: Heldin, CH, 2008-11-23 19:29:34
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Grb7 binds to the active PDGF receptor
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