Source:http://www.reactome.org/biopax/48887BiochemicalReaction3114
| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
Authored: Garapati, P V, Jassal, B, 2008-11-24 10:14:27,
Edited: Garapati, P V, Jassal, B, 2008-11-24 10:14:27,
Nck is a widely expressed protein consisting exclusively of SH2 and SH3 domains. With its SH2 doamin Nck interacts with Tyr571 of the PDGF beta-receptor and it also interacts with the alpha-receptor, but the sites of interaction has not been determined. Nck is involved in the activation of the JNK serine/threonine kinase through interaction with the serine/threonine kinases PAK1 and NIK.,
Reviewed: Heldin, CH, 2008-11-23 19:29:34
|
| biopax3:xref | |
| biopax3:dataSource | |
| biopax3:displayName |
Nck binds to the active PDGF receptor
|
| biopax3:left | |
| biopax3:right |