Source:http://www.reactome.org/biopax/48887BiochemicalReaction3108
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Authored: Garapati, P V, Jassal, B, 2008-11-24 10:14:27,
Edited: Garapati, P V, Jassal, B, 2008-11-24 10:14:27,
GTPase-activating protein (GAP) has two SH2 domains which bind only to PDGF beta-receptors on Tyr771. GAP does not bind the alpha-receptor. GAP converts Ras-GTP to Ras-GDP, deactivating Ras.,
Reviewed: Heldin, CH, 2008-11-23 19:29:34
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GAP binds to PDGF-beta receptors only
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