Source:http://www.reactome.org/biopax/48887BiochemicalReaction3101
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Authored: Garapati, P V, Jassal, B, 2008-11-24 10:14:27,
Edited: Garapati, P V, Jassal, B, 2008-11-24 10:14:27,
PI3K's preferred substrate is phosphatidylinositol 4,5-bisphosphate [PI(4,5)P2] which is phosphorylated to the trisphosphate [PI(3,4,5)P3]. PI3-kinase and its products have been found to be of importance in PDGF-stimulated actin reorganization, and directed cell movement, as well as in the stimulation of cell growth and inhibition of apoptosis.,
Reviewed: Heldin, CH, 2008-11-23 19:29:34
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PI3K catalyses the phosphorylation of PIP2 to PIP3
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2.7.1.153
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