Source:http://www.reactome.org/biopax/48887BiochemicalReaction2976
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Activated AMPK (phosphorylated on Thr172/Thr174 and AMP bound) phosphorylates Raptor on Ser 722 and Ser 792. These phosphorylations are required for inhibition of mTORC1 activity in response to energy stress (Gwinn DM et al, 2008).,
Authored: Katajisto, P, Makela, T, Wu, J, 2010-02-03,
Edited: Jassal, B, 2009--1-1-,
Reviewed: Zheng, B, 2009-10-20
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AMPK phosphorylates Raptor
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