Source:http://www.reactome.org/biopax/48887BiochemicalReaction2975
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Authored: Katajisto, P, Makela, T, Wu, J, 2008--1-1-,
Edited: Jassal, B, 2008-11-19 15:14:38,
If AMP:ATP ratio rises, AMP (instead of ATP) is bound by the AMPK-gamma subunit, which inhibits the dephosphorylation of the AMPK-alpha subunit resulting in activation of AMPK. It is not clear, as of yet, whether AMP binds to unphosphorylated AMPK.,
Reviewed: Zheng, B, 2009-10-20
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Phosphorylated AMPK binds AMP
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