Source:http://www.reactome.org/biopax/48887BiochemicalReaction2930
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Authored: Herington, AC, 2011-06-13,
Edited: Jupe, S, 2011-06-10,
GHBP, the ectodomain of GHR cleaved from membrane-bound GHR can form a heterodimer with GHR. This is not capable of signaling and may be a negative regulatory influence. GHBP can also inhibit signaling by competing with the full length receptor for GH binding.,
Reviewed: Waters, MJ, 2011-06-23
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GHBP binds GHR
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