Source:http://www.reactome.org/biopax/48887BiochemicalReaction2906
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Authored: Jupe, S, 2010-10-14,
Edited: Jupe, S, 2011-06-10,
Human growth hormone (GH) is a heterogeneous protein hormone consisting of several isoforms. The peptide is encoded by 2 genes, GH1 and GH2, both give rise to multiple variant forms. Post-translational modification including oligomerization increases the variation (Baumann 2009). Approximately 14% of circulating human Growth Hormone (GH) is in dimer or oligomer form, this number varying from 0 to 100% (Kublickas et al. 2006). The biological activity of these oligomeric forms is variably diminished when compared to the monomer (Baumann 2009).,
Reviewed: Herington, AC, 2011-06-13,
Reviewed: Waters, MJ, 2011-06-23
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Growth hormone forms dimers and oligomers
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