Source:http://www.reactome.org/biopax/48887BiochemicalReaction2748
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Authored: Garapati, P V, 2010-07-07,
Edited: Garapati, P V, 2010-07-07,
Reviewed: Abdul-Sater, AA, Schindler, C, 2010-08-17,
STAT2 recruited to the IFNAR1 subunit then becomes tyrosine phosphorylated on residue 690 by TYK2 kinase. This phosphotyrosine provides a docking site for recruitment of STAT1 to IFNAR1, which is then tyrosine phosphorylated and activated.
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Phosphorylation of STAT2
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2.7.10
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