Source:http://www.reactome.org/biopax/48887BiochemicalReaction2714
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Authored: Garapati, P V, 2010-08-02,
Edited: Garapati, P V, 2010-08-02,
NLRC5 competes with IPS-1 for binding to the CARD domain of RIG-I/MDA5. NLRC5 specifically recognize the CARD domains of RIG-I/MDA5 when the CARD domains become accessible after viral infection, leading to dampened activation of IRF3.,
Reviewed: Kawai, T, Akira, S, 2010-10-30
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NLRC5 interacts with RIG-I/MDA5 and inhibit IPS-1 binding
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