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Authored: Garapati, P V, 2010-08-02, Edited: Garapati, P V, 2010-08-02, Reviewed: Kawai, T, Akira, S, 2010-10-30, TRAF6 requires MEKK1 to activate NF-kB and MEKK1 may interact with TRAF6, which in turn contribute to the activation of IKK and MAPKK, leading to the activation of NF-kB and AP-1. (Yoshida et al)
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Interaction of MEKK1 with TRAF6
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