Source:http://www.reactome.org/biopax/48887BiochemicalReaction263
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Authored: D'Eustachio, P, 2008-11-29 15:41:00,
Edited: D'Eustachio, P, 2008-11-29 15:41:00,
KARS (cytosolic lysyl tRNA synthetase) catalyzes the reaction of lysine, tRNA(Lys), and ATP to form Lys-tRNA(Lys), AMP, and pyrophosphate. The enzyme, a class II tRNA synthetase, is a homodimer found in the cell as a component of the mutienzyme aminoacyl-tRNA synthetase complex. The same gene encodes both cytosolic and mitochondrial KARS enzymes (Shiba et al. 1997).,
Reviewed: Antonellis, A, 2008-12-02 16:58:45
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lysine + tRNA(Lys) + ATP => Lys-tRNA(Lys) + AMP + pyrophosphate
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6.1.1.6
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