Source:http://www.reactome.org/biopax/48887BiochemicalReaction2610
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Authored: Jupe, S, 2010-10-26,
Edited: Jupe, S, 2010-11-01,
Factor H (FH) binds to C3bBb, leading to displacement of Bb. Complement factor H-related protein 3 (FHR-3) has also been reported to bind C3Bb leading to inhibition of C3Bb C3 convertase activity (Fritsche et al. 2010). FH also acts as a cofactor for the factor I-mediated proteolytic inactivation of C3b to iC3b.,
Reviewed: Bradley, DT, 2012-02-13,
Reviewed: Fraczek, LA, 2012-02-13
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Factor H binds to C3bBb
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