Source:http://www.reactome.org/biopax/48887BiochemicalReaction2595
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Authored: de Bono, B, 2006-07-21 15:55:23,
Edited: Jupe, S, 2010-11-17,
Factor D, a constitutively active serine protease found in trace amounts in the blood, cleaves a specific Arg-Lys bond in the Factor B component of the cell surface-associated C3b:Factor B complex, yielding the alternate C3 convertase C3bBb on the surface and releasing an inactive polypeptide, Factor Ba (Lesavre and Muller-Eberhard 1978; Lesavre et al. 1979; Schreiber et al. 1978).,
Reviewed: D'Eustachio, P, 2006-08-28 21:16:15
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Factor D cleaves C3b-bound Factor B
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3.4.21
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