Source:http://www.reactome.org/biopax/48887BiochemicalReaction2571
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Authored: Shamovsky, V, 2010-06-01,
Edited: Shamovsky, V, 2010-09-22,
IRAK4 deficient macrophages fail to induce IRAK2 phosphorylation (Kawagoe et al. 2008), suggesting that activated IRAK4 phosphorylates IRAK2 as it does IRAK1.<p>Phosphorylation sites of IRAK2 remain to be characterized.,
Reviewed: Gillespie, ME, 2010-11-30
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Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomer:Mal:activated TLR complex
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