Source:http://www.reactome.org/biopax/48887BiochemicalReaction2511
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biopax3:comment |
Authored: Shamovsky, V, 2012-04-26,
Edited: Shamovsky, V, 2012-05-25,
Reviewed: D'Eustachio, P, 2012-05-25,
TRIF signaling activates TRAF3 self-mediated polyubiquitination trough Lys-63 of ubiquitin. The ubiquitinated TRAF3 in turn activates the interferon response [Tseng PH et al 2010].
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Auto-ubiquitination of TRAF3
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6.3.2.19
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