Source:http://www.reactome.org/biopax/48887BiochemicalReaction2478
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Authored: Shamovsky, V, 2010-06-01,
Edited: Shamovsky, V, 2011-08-12,
Polyubiquitinated TRAF6 (as E3 ubiquitin ligase) generates free K63 -linked polyubiquitin chains that non-covalently associate with ubiquitin receptors of TAB2/TAB3 regulatory proteins of the TAK1 complex, leading to the activation of the TAK1 kinase.,
Reviewed: Gillespie, ME, 2010-11-30
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Activated TRAF6 synthesizes unanchored polyubiquitin chains
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6.3.2.19
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