Source:http://www.reactome.org/biopax/48887BiochemicalReaction2448
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Authored: Akkerman, JW, 2009-06-03,
Edited: Jupe, S, 2010-09-01,
Reviewed: Heemskerk, JW, 2010-09-01,
cGMP and cAMP dependent protein kinases (PKG and PKA respectively) phosphorylate the Rap1 GTPase activating RAP1GAP2 at serine 7 (Schultess et al. 2007). This reduces the binding of inhibitory 14-3-3 proteins to RAP1GAP2.
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PKA/PKG phosphorylate Rap1GAP2
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2.7.11
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