Source:http://www.reactome.org/biopax/48887BiochemicalReaction2402
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Authored: Garapati, P V, 2012-02-21,
Edited: Garapati, P V, 2012-02-21,
Immediately after assembly in the ER nonameric (alpha beta:Ii)3 complexes egress from ER, facilitated by the presence of Ii, and enter the Golgi complex (Wolf & Ploegh 1995, Geuze 1998). Incorrectly folded or oligomerized alpha, beta and Ii chains are retained in the ER and degraded. The Sec23/24-Sar1 pre-budding complex binds to the nonameric complex and then recruits Sec13/31 outer shell, which buds off from the membrane as a coat protein complex II (COPII) vesicle to be transported to the Golgi complex (Bickford et al. 2004).,
Reviewed: Neefjes, Jacques, 2012-05-14
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| biopax3:xref |
http://identifiers.org/pubmed/11790530,
http://identifiers.org/pubmed/15093828,
http://identifiers.org/pubmed/19703008,
http://identifiers.org/pubmed/2391366,
http://identifiers.org/pubmed/8689559,
http://identifiers.org/pubmed/9639994,
urn:biopax:UnificationXref:REACTOME DATABASE ID_2130731,
urn:biopax:UnificationXref:REACTOME_REACT_120802_1
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Formation of COPII vesicle
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